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GULLIAN BAIRRE SYNDROME

Gbs is d comonest acute polyneuropathy presumed to b autoimune.,afect people at any age,folows viral inf,after surgery or rabies immunization
pathology
monophasic mediatd inflamatory f peripheral n.Multifocal demylination result n conductn block,secondary axonal deg.

C/f
acute disorder,progres for few days,motor neuropathy,sensory findings minimum,distal paraesthesia,motor paralysis,absent reflexes,bifacial weaknes,resp paralysis,suden fluctuatn in bp n heart rate,blader inv rare

investigation
csf become abn aftr 1wk raised proteins,normal sugar,cell count upto 50 cells/mmc
nerve conductn velocity slow
acute intermitent porphyria

Rx
maintaine a b c
ventilate
monitor pulse bp cardiac activity
steroids
plasmapheresis
gama globulin 0.4g/kg/d for 5days



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